Saudi Retina Group Retina Treatments

3

Jan

FDA Approves First Ever Treatment for Geographic Atrophy due to Age-Related Macular Degeneration (AMD)

At Austin Retina Associates, we take pride in being able to offer our patients the latest advancements in treatment for many common and complex eye conditions affecting the retina. One new therapy that has recently earned approval from the U.S. Food and Drug Administration (FDA) to treat geographic atrophy from age-related macular degeneration (AMD) is SYFOVRE, which our team of board-certified retinal specialists is excited to start offering to certain AMD patients in the coming months. What is Age-Related Macular Degeneration (AMD)? AMD is the leading cause of blindness for adults in the United States, affecting approximately 11 million people. AMD occurs due to an age-related accumulation of cellular debris underneath the retina (known as drusen) as well as the loss or degeneration of retinal tissue (known as geographic atrophy). This process describes “dry” AMD which represents approximately 90% of all cases of AMD, and can be classified as early, intermediate, or advanced depending on the severity. Occasionally, new blood vessels from a tissue layer underneath the retina called the choroid may leak or bleed in a process known as “wet” AMD. The new blood vessels are called “choroidal neovascularization” (CNV) and are the hallmark of wet AMD. What is Geographic Atrophy associated with AMD? Approximately 20% of patients with AMD will develop geographic atrophy, an advanced form of dry AMD causing progressive loss of healthy retinal tissue over time. This results in a permanent reduction of visual acuity and central visual field. “While there are currently several clinical trials investigating therapies for geographic atrophy including offerings from Austin Retina, there was previously no FDA-approved treatment available to patients with this condition,” explains retina specialist Dr. Edward Wood. SYFOVRE (pegcetacoplan), manufactured by Apellis Pharmaceuticals, was approved in February 2023 and is considered the first effective treatment for geographic atrophy in AMD. How effective is SYFOVRE? Clinical studies have shown that intravitreal injections of SYFOVRE every one to two months are effective at reducing the rate of enlarged areas of atrophy in the macula by approximately 20%, and that this effect may increase the longer it is used. This medication was developed based on evidence that genetic changes associated with a key component of inflammation called the “complement cascade” play a role in AMD. SYFOVRE targets a key component of the complement cascade called C3, thereby reducing the progression of geographic atrophy. How is SYFOVRE administered? SYFOVRE is injected into the gel-like part of the eye (vitreous) every 25 to 60 days as directed by one of our Austin Retina Associates physicians. What does this mean for patients? Our retina specialists explain that “for many patients with geographic atrophy encroaching on their central vision, any reduction in the rate of progression offered by this treatment may translate to years of preserved functional vision.” They add that “continued advances in therapy have allowed us to limit vision loss in the vast majority of patients affected by wet macular degeneration. However, until now, there has been little to offer our many patients with vision loss from advanced dry AMD.” Patients will be relieved to know that SYFOVRE is now a successful treatment option that we can help you with at Austin Retina Associates.

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Saudi Retina Group Retina Surgery

2

Jan

What Surgical Procedures Does a Retina Surgeon Perform?

At Austin Retina Associates, we treat many common and complex eye conditions affecting the retina. Often, surgery is the most effective way to correct these issues to improve or restore a patient’s sight, and ultimately, quality of life. Our retina specialists in Austin are highly respected for their top-quality care not only in Central Texas, but throughout the nation as well. Retinal Surgery in Austin Our board-certified vitreoretinal surgeons have extensive training and experience in advanced retinal surgical techniques. Some of the surgeries and procedures we perform frequently include: Vitrectomy: A vitrectomy is when the vitreous humor gel that fills the eye cavity is removed to provide better access for retinal repair . Different forms of vitrectomy include: Vitrectomy with laser for retinal detachment and vitreous hemorrhage Vitrectomy with membrane stripping for epiretinal membrane or macular holes Vitrectomy with repositioning, removal, or insertion of intraocular lens Vitrectomy with cataract extraction from pars plana approach Scleral Buckle: A scleral buckle is a small, flexible band used to help gently squeeze and reattach the retina when it becomes detached. It is delicately secured into place around the eyeball via surgery. This may be performed with or without a vitrectomy. Laser Surgery or Cryotherapy: Each of these surgical treatments is used to repair retinal tears, holes, or detachments. With laser surgery (also known as photocoagulation), laser-focused heat is administered to the injury site creating tiny scars which will then promote healing. In a similar manner, freezing the area around the retina injury or detachment (cryotherapy) will also create tiny scars that then promote eventual healing and reattachment. Pneumatic Retinopexy: In pneumatic retinopexy, a small air bubble is gently injected into the eye in order to coerce the retina back into place following detachment. Intravitreal Injection: Intravitreal injections are done when medication needs to be deposited precisely into the far back space of the eye called the vitreous cavity. Conditions such as age-related macular degeneration (AMD), diabetic retinopathy, and retinal vein occlusions often require medication to be administered this way. Other procedures that we perform at Austin Retina Associates include: Radiation plaque implant and removal Repair of ruptured globe Removal of foreign body Anterior chamber paracentesis Indirect focal laser Indirect panretinal laser Retina Treatment Centers The majority of the procedures we perform are conveniently done in one of our 15 Central Texas retina centers using local anesthesia. Surgical procedures that are more complex and require anesthesia will be done in a hospital or surgery center, but rarely require an overnight stay. After your procedure is complete, your retina specialist will give specific instructions needed for the care and healing of your eye in the days to come. Consult With a Retina Surgeon in Austin Today If you suspect you are suffering from a retina condition, have experienced an eye injury, or have been referred to us by another physician, our retinal surgeons are available 24/7 to provide advanced treatment and procedures at one of our retina treatment centers in Austin.

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Saudi Retina Group Retina Research

1

Jan

Why Should I Participate in a Clinical Trial?

At Austin Retina Associates, we understand that there are a number of misconceptions patients may have about what it means to participate in a clinical trial. These misconceptions are unsurprising, as clinical trials, particularly modern ones, are not part of our normal, everyday conversations. We hope that the information below will help describe the reality of being in a clinical trial and the many potential benefits of the process. Of course, if you have questions or are interested in a specific clinical trial with our practice, please contact our staff today. What is a clinical trial? And are they safe? Clinical trials are scientific medical research initiatives into the appropriateness, effectiveness and safety of new treatments in humans. The goal of a clinical trial, whether for a vision-related issue or other health problem, is to improve patient care and advance medical knowledge. And yes, they are safe as long as they are conducted by reputable, experienced organizations, such as Austin Retina Associates. Why do clinical trials exist? Clinical trials present an opportunity for patients to try medications and treatments that might not otherwise be available because the scientific community is not yet fully confident in their success (e.g. not yet FDA approved), but believe that the highest possible quality of data can be achieved while ensuring patient safety. This means that, at the completion of the trial, those involved will have possibly found successful treatment and such treatment can move forward toward use for the general population. Here are some core benefits to clinical trial participation at Austin Retina: Participants will (potentially) have access to the newest and most advanced drug(s) ahead of FDA approval. The “worst case scenario” for participation is that a patient would receive standard care. Participants enjoy “extra” care as being involved in a trial includes additional blood testing or imagining – all of which are carefully monitored by the trial’s clinical team. There is no cost to the patient – ever. Patients might even receive a stipend. Patients are connected with a main coordinator throughout the trial for every visit over the course of 6/12/24 months – A true VIP experience. A trial is an opportunity to receive potential treatment when no other remedy is currently available. Who is a good candidate for a clinical trial? The answer to this is very dependent on the type of clinical trial being offered and the symptoms and condition a patient is experiencing. For example, a patient may have condition “X” but not display any symptoms relating to a specific clinical trial, so they would not be a good fit for that trial. Of course, your doctor is the best resource for advice regarding clinical trials that are applicable to your individual situation. We recommend that you connect with your doctor in order to determine whether there is a trial you can participate in. Your doctor will only recommend a trial if he or she believes it will be of significant benefit to your health – having someone enter into a clinical trial is not taken lightly or without real consideration. How do I find out whether I can participate in a clinical trial? As noted, your doctor is the one to talk to about participating in a clinical trial. At Austin Retina, we frequently enroll patients in open clinical trials when possible. Sometimes, a clinical trial can reach capacity and we are unable to continue enrollment. You can learn more about trials that are currently open for enrollment here. You can also contact our office to ask about clinical trial participation today.

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Saudi Retina Group Retina Conditions

10

May

Are Floaters In My Vision A Concern?

What are eye floaters? Eye floaters are typically caused by tiny bits of debris, such as collagen fibers or clumps of protein, that float in the gel-like substance (vitreous humor) inside your eye. They cast shadows on the retina, creating the perception of floaters. Should I be concerned? There are instances where floaters could be indicative of a more serious condition. If you suddenly experience a significant increase in the number of floaters, notice flashes of light, or have a loss of peripheral (side) vision, it is recommended to seek prompt medical attention. While floaters can be bothersome or distracting, they are often harmless and tend to become less noticeable over time. What might be causing my floaters? These symptoms may be associated with a retinal tear or detachment, which can require immediate treatment to prevent vision loss. Additionally, if floaters are accompanied by other concerning symptoms like eye pain, redness, or changes in vision, it is advisable to consult an eye care professional for evaluation and appropriate guidance. In general, occasional floaters that do not interfere significantly with your vision are considered normal. However, it is always prudent to consult an eye care specialist to rule out any underlying issues and ensure your eye health is properly assessed.

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Saudi Retina Group Retina Conditions

4

Mar

What Eye Problems Can Diabetes Cause?

What Eye Problems Can Diabetes Cause? Posted on July 21, 2022 by Austin Retina Associates in Retina Conditions If left untreated and unmanaged, diabetes can cause a myriad of health problems, including serious vision issues. Did you know that diabetic retinopathy is the leading cause of blindness in adults ages 20-74? If you have diabetes, it’s crucial to make diabetic eye exams a regular part of your healthcare routine to help prevent or manage diabetes-related eye diseases. Early diagnosis and treatment is important to help protect your eyesight. What conditions do diabetic eye specialists treat? If you have diabetes, there are many diseases that you are susceptible to, including: Diabetic Retinopathy One of the main eye diseases that diabetics can develop, diabetic retinopathy is a progressive eye disease that is characterized by the presence of weakened, fragile, and damaged blood vessels in the retina. Symptoms may not be noticeable in the beginning stages of this disease, but advanced stages can cause bleeding inside the eye and scar tissue formation that can lead to sight-threatening tractional retinal detachments. Diabetic Macular Edema When the abnormal blood vessels caused by diabetic retinopathy leak fluid into the central portion of the retina, it is known as diabetic macular edema. As the fluid gathers, the central portion of the retina begins to swell. This will typically decrease your central reading vision and, if not treated properly, can lead to permanent central vision loss. Glaucoma You may have heard of glaucoma, as it is one of the most common causes of permanent vision loss in older adults. But did you know that diabetics are twice as likely to develop this condition? Glaucoma is defined by damage to the optic nerve caused by excessive pressure within the eye and can cause a variety of symptoms, including: Eye pain Blurred vision Halos around lights Headaches, Blind spots in central or peripheral vision Cataracts Cataracts are a common eye condition in which the ocular lens becomes cloudy. They typically develop slowly over time and can impair vision in several ways, including: Blurriness Dulled color perception Double vision Light sensitivity Poor night vision Other Retinal Conditions There are many other retinal conditions that diabetes can increase your risk for developing. These include: Wet Age-Related Macular Degeneration - A disease in which the macula deteriorates, and abnormal neovascularization occurs. Retinal Vein and Artery Occlusions - A group of conditions that cause issues in the retinal vascular system. Retinal Detachment – A serious eye condition in which the retina has separated from the underlying layers of the eye.

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Saudi Retina Group Retina Conditions

9

Sep

How Diabetes Impacts Vision and Retinal Health?

It’s estimated that over 34 million adults in the United States have some form of diabetes. While it’s common knowledge that patients with diabetes must keep their blood glucose, blood pressure, and cholesterol levels in check, many people may not realize that patients with diabetes must also pay extra close attention to their vision and retinal health. Because diabetes can affect the entire vascular system, the eyes are extremely vulnerable to a number of vision-threatening conditions, including diabetic retinopathy, diabetic macular edema, glaucoma, and cataracts. Diabetic Retinopathy Diabetic retinopathy is a condition in which high levels of blood glucose cause damage to blood vessels in the retina. Diabetic retinopathy can affect patients with either type 1 or type 2 diabetes. Pregnant women with gestational diabetes are also at risk of developing diabetic retinopathy. In its earliest stages, diabetic retinopathy typically doesn’t cause any noticeable symptoms. However, as time goes on and blood vessel damage progresses, patients become increasingly likely to lose their vision forever. Diabetic Macular Edema Diabetic macular edema (DME) is a complication of diabetic retinopathy that occurs when fluid accumulates in the macula, which is the central portion of the retina. The macula controls our central vision and enables us to perform complex vision tasks such as reading, driving, and seeing in fine detail. When abnormal or damaged blood vessels in the retina leak into the macula, that can significantly disrupt vision and even lead to permanent vision loss. Glaucoma Glaucoma is an umbrella term used to describe various sub-conditions that cause structural damage to the optic nerve. This damage is typically caused by extremely high pressure in the eyes. Glaucoma can affect one or both eyes, and if left untreated, eventually leads to permanent vision loss. Because patients with diabetes often have to keep their blood pressure in check, diabetes is considered one of the many risk factors for developing glaucoma. The chances of developing glaucoma become even higher for patients who have diabetic retinopathy. Cataracts Cataracts occur when clumps of protein accumulate in the eye and are characterized by the appearance of a semi-opaque, cloudy area over the lens of the eye. As the condition progresses, light is unable to fully enter the eye. As a result, it becomes increasingly challenging for the retina to receive light and convert it into signals for the brain to interpret as images; this is another form of vision loss. For patients with diabetes, cataracts are typically caused by excessively high levels of blood sugar. Diabetic Eye Disease Prevention In many cases, the most severe and permanent effects of diabetic eye diseases can be staved off with preventive measures. These include: Managing blood glucose levels Maintaining healthy cholesterol and blood pressure levels Maintaining a healthy diet Exercising regularly Not smoking One of the most important things that patients with diabetes should do for their vision health is get a comprehensive diabetic eye exam at least once a year from a diabetic eye specialist. The earlier a doctor catches and diagnoses diabetic eye diseases, the more likely the patient is to have a decent chance of recovery.

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